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Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants
Molecular modeling has been employed in the search for lead compounds of chemotherapy to fight cancer. In this study, pharmacophore models have been generated and validated for use in virtual screening protocols for eight known anticancer drug targets, including tyrosine kinase, protein kinase B β,...
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| Publicado en: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Dove Medical Press
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4938243/ https://ncbi.nlm.nih.gov/pubmed/27445461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S108118 |
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