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Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants

Molecular modeling has been employed in the search for lead compounds of chemotherapy to fight cancer. In this study, pharmacophore models have been generated and validated for use in virtual screening protocols for eight known anticancer drug targets, including tyrosine kinase, protein kinase B β,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: Ntie-Kang, Fidele, Simoben, Conrad Veranso, Karaman, Berin, Ngwa, Valery Fuh, Judson, Philip Neville, Sippl, Wolfgang, Mbaze, Luc Meva’a
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938243/
https://ncbi.nlm.nih.gov/pubmed/27445461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S108118
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