CYP2C19 loss-of-function alleles are not associated with clinical outcome of clopidogrel therapy in patients treated with newer-generation drug-eluting stents

CYP2C19 loss-of-function (LOF) alleles adversely affect clinical outcome of clopidogrel therapy. Recent introduction of a newer-generation drug-eluting stent (DES) has significantly reduced the occurrence of stent thrombosis. The aim of this study was to evaluate the impact of CYP2C19 LOF alleles on...

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Dettagli Bibliografici
Pubblicato in:Medicine (Baltimore)
Autori principali: Choi, Ik Jun, Koh, Yoon-Seok, Park, Mahn-Won, Her, Sung Ho, Choi, Yun-Seok, Park, Chul-Soo, Park, Hun-Jun, Kim, Pum-Joon, Chung, Wook-Sung, Kim, Ho-Sook, Shin, Jae-Gook, Seung, Ki-Bae, Chang, Kiyuk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Health 2016
Soggetti:
3400
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937952/
https://ncbi.nlm.nih.gov/pubmed/27368038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000004049
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