Over 20% (15)N Hyperpolarization in Under One Minute for Metronidazole, an Antibiotic and Hypoxia Probe

[Image: see text] Direct NMR hyperpolarization of naturally abundant (15)N sites in metronidazole is demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in SHield Enables Alignment Transfer to Heteronuclei). In only a few tens of seconds, nuclear spin polarization P((15)N) o...

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Publié dans:J Am Chem Soc
Auteurs principaux: Barskiy, Danila A., Shchepin, Roman V., Coffey, Aaron M., Theis, Thomas, Warren, Warren S., Goodson, Boyd M., Chekmenev, Eduard Y.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2016
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937835/
https://ncbi.nlm.nih.gov/pubmed/27321159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04784
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