Micron-sized and submicron-sized aerosol deposition in a new ex vivo preclinical model

BACKGROUND: The knowledge of where particles deposit in the respiratory tract is crucial for understanding the health effects associated with inhaled drug particles. METHOD: An ex vivo study was conducted to assess regional deposition patterns (thoracic vs. extrathoracic) of radioactive polydisperse...

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Bibliographic Details
Published in:Respir Res
Main Authors: Perinel, Sophie, Leclerc, Lara, Prévôt, Nathalie, Deville, Agathe, Cottier, Michèle, Durand, Marc, Vergnon, Jean-Michel, Pourchez, Jérémie
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937580/
https://ncbi.nlm.nih.gov/pubmed/27388488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0395-7
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