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Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks

The complex language of eukaryotic gene expression remains incompletely understood. Despite the importance suggested by many noncoding variants statistically associated with human disease, nearly all such variants have unknown mechanisms. Here, we address this challenge using an approach based on a...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Kelley, David R., Snoek, Jasper, Rinn, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937568/
https://ncbi.nlm.nih.gov/pubmed/27197224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.200535.115
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