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Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks

The complex language of eukaryotic gene expression remains incompletely understood. Despite the importance suggested by many noncoding variants statistically associated with human disease, nearly all such variants have unknown mechanisms. Here, we address this challenge using an approach based on a...

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Podrobná bibliografie
Vydáno v:Genome Res
Hlavní autoři: Kelley, David R., Snoek, Jasper, Rinn, John L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937568/
https://ncbi.nlm.nih.gov/pubmed/27197224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.200535.115
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