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Elevated variant density around SV breakpoints in germline lineage lends support to error-prone replication hypothesis
Copy number variants (CNVs) are a class of structural variants that may involve complex genomic rearrangements (CGRs) and are hypothesized to have additional mutations around their breakpoints. Understanding the mechanisms underlying CNV formation is fundamental for understanding the repair and muta...
Sparad:
| I publikationen: | Genome Res |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937565/ https://ncbi.nlm.nih.gov/pubmed/27216746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.205484.116 |
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