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A Novel Quantitative Mass Spectrometry Platform for Determining Protein O-GlcNAcylation Dynamics

Over the past decades, protein O-GlcNAcylation has been found to play a fundamental role in cell cycle control, metabolism, transcriptional regulation, and cellular signaling. Nevertheless, quantitative approaches to determine in vivo GlcNAc dynamics at a large-scale are still not readily available....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Wang, Xiaoshi, Yuan, Zuo-Fei, Fan, Jing, Karch, Kelly R., Ball, Lauren E., Denu, John M., Garcia, Benjamin A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937517/
https://ncbi.nlm.nih.gov/pubmed/27114449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.049627
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