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Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage

Lineage-specific transcription factors determine the cell fate during development. Direct conversion of several cell types into other lineages has been achieved by the overexpression of specific transcription factors. Even cancer cells have been demonstrated to be amenable to transdifferentiation. H...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fehrenbach, Sabrina, Novak, Daniel, Bernhardt, Mathias, Larribere, Lionel, Boukamp, Petra, Umansky, Viktor, Utikal, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937495/
https://ncbi.nlm.nih.gov/pubmed/27387763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28891
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