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Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage

Lineage-specific transcription factors determine the cell fate during development. Direct conversion of several cell types into other lineages has been achieved by the overexpression of specific transcription factors. Even cancer cells have been demonstrated to be amenable to transdifferentiation. H...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Fehrenbach, Sabrina, Novak, Daniel, Bernhardt, Mathias, Larribere, Lionel, Boukamp, Petra, Umansky, Viktor, Utikal, Jochen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937495/
https://ncbi.nlm.nih.gov/pubmed/27387763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28891
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