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Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion

Abstract Melanoma is an aggressive skin cancer and highly lethal at advanced stages due to its high tumorigenicity and metastatic capacity. Changing the phenotype of cancer cells from one lineage to another, a process called transdifferentiation, leads to tumor cell reversion, which goes along with...

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Detalhes bibliográficos
Principais autores: Yiman Wang, Ke Liu, Yuxin Zhang, Daniel Novak, Aniello Federico, Cai Xu, Sandra Horschitz, Marlene Vierthaler, Qian Sun, Nina Wang, Juliane Poelchen, Tamara Steinfass, Laura Hüser, Moritz Mall, Viktor Umansky, Jochen Utikal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2025-07-01
coleção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-025-07863-y
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