Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion

Abstract Melanoma is an aggressive skin cancer and highly lethal at advanced stages due to its high tumorigenicity and metastatic capacity. Changing the phenotype of cancer cells from one lineage to another, a process called transdifferentiation, leads to tumor cell reversion, which goes along with...

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Hlavní autoři:	Yiman Wang, Ke Liu, Yuxin Zhang, Daniel Novak, Aniello Federico, Cai Xu, Sandra Horschitz, Marlene Vierthaler, Qian Sun, Nina Wang, Juliane Poelchen, Tamara Steinfass, Laura Hüser, Moritz Mall, Viktor Umansky, Jochen Utikal
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2025-07-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-025-07863-y
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