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Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria

Any pathogen population sufficiently large is expected to harbor spontaneous drug-resistant mutants, often responsible for disease relapse after antibiotic therapy. It is seldom appreciated, however, that while larger populations harbor more mutants, the abundance distribution of these mutants is ex...

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Publicat a:Genetics
Autors principals: Couce, Alejandro, Rodríguez-Rojas, Alexandro, Blázquez, Jesús
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937460/
https://ncbi.nlm.nih.gov/pubmed/27182949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.185355
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