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Transcriptional reprogramming of metabolic pathways in critically ill patients
BACKGROUND: Critical illness causes a shift away from mitochondrial metabolism towards a greater dependence on glycolysis. This metabolic shift is thought to be associated with lactic acidosis, organ dysfunction and poor clinical outcomes. The current paradigm is that low oxygen supply causes region...
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| Veröffentlicht in: | Intensive Care Med Exp |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936987/ https://ncbi.nlm.nih.gov/pubmed/27387528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-016-0094-1 |
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