Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake

BACKGROUND: Though overexpression of epidermal growth factor receptor (EGFR) in several forms of cancer is considered to be an important prognostic biomarker related to poor prognosis, clear correlations between biomarker assays and patient management have been difficult to establish. Here, we utili...

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Bibliographic Details
Published in:EJNMMI Res
Main Authors: Cheng, Qing, Wållberg, Helena, Grafström, Jonas, Lu, Li, Thorell, Jan-Olov, Hägg Olofsson, Maria, Linder, Stig, Johansson, Katarina, Tegnebratt, Tetyana, Arnér, Elias S. J., Stone-Elander, Sharon, Ahlzén, Hanna-Stina Martinsson, Ståhl, Stefan
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936982/
https://ncbi.nlm.nih.gov/pubmed/27388754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0213-8
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