[(68)Ga]ABY-028: an albumin-binding domain (ABD) protein-based imaging tracer for positron emission tomography (PET) studies of altered vascular permeability and predictions of albumin-drug conjugate transport

BACKGROUND: Albumin is commonly used as a carrier platform for drugs to extend their circulatory half-lives and influence their uptake into tissues that have altered permeability to the plasma protein. The albumin-binding domain (ABD) protein, which binds in vivo to serum albumin with high affinity,...

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Vydáno v:EJNMMI Res
Hlavní autoři: Jussing, Emma, Lu, Li, Grafström, Jonas, Tegnebratt, Tetyana, Arnberg, Fabian, Rosik, Helena Wållberg, Wennborg, Anders, Holmin, Staffan, Feldwisch, Joachim, Stone-Elander, Sharon
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509035/
https://ncbi.nlm.nih.gov/pubmed/32960353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00694-2
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