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Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces

Tightly controlled recruitment of telomerase, a low-abundance enzyme, to telomeres is essential for regulated telomere synthesis. Recent studies in human cells revealed that a patch of amino acids in the shelterin component TPP1, called the TEL-patch, is essential for recruiting telomerase to telome...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Hu, Xichan, Liu, Jinqiang, Jun, Hyun-IK, Kim, Jin-Kwang, Qiao, Feng
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936895/
https://ncbi.nlm.nih.gov/pubmed/27253066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15470
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