The Treponema denticola FhbB Protein Is a Dominant Early Antigen That Elicits FhbB Variant-Specific Antibodies That Block Factor H Binding and Cleavage by Dentilisin

The Treponema denticola FhbB protein contributes to immune evasion by binding factor H (FH). Cleavage of FH by the T. denticola protease, dentilisin, may contribute to the local immune dysregulation that is characteristic of periodontal disease (PD). Although three FhbB phyletic types have been defi...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Miller, Daniel P., Oliver, Lee D., Tegels, Brittney K., Reed, Lucas A., O'Bier, Nathaniel S., Kurniyati, Kurni, Faust, Lindsay A., Lawson, Christine K., Allard, Anna M., Caimano, Melissa J., Marconi, Richard T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936362/
https://ncbi.nlm.nih.gov/pubmed/27113359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01542-15
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