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EGFR gene amplification is relatively common and associates with outcome in intestinal adenocarcinoma of the stomach, gastro-oesophageal junction and distal oesophagus

BACKGROUND: Approximately 50 % of gastric adenocarcinomas belong to a molecular subgroup characterised by chromosomal instability and a strong association with the intestinal histological subtype. This subgroup typically contains alterations in the receptor tyrosine kinase–RAS pathway, for example E...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Birkman, Eva-Maria, Ålgars, Annika, Lintunen, Minnamaija, Ristamäki, Raija, Sundström, Jari, Carpén, Olli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936304/
https://ncbi.nlm.nih.gov/pubmed/27387915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2456-1
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