Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens

BACKGROUND: MammaTyper is a novel CE-marked in vitro diagnostic RT-qPCR assay which assigns routinely processed breast cancer specimens into the molecular subtypes Luminal A-like, Luminal B-like (HER2 positive or negative), HER2 positive (non-luminal) and Triple negative (ductal) according to the mR...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Laible, Mark, Schlombs, Kornelia, Kaiser, Katharina, Veltrup, Elke, Herlein, Stefanie, Lakis, Sotiris, Stöhr, Robert, Eidt, Sebastian, Hartmann, Arndt, Wirtz, Ralph M., Sahin, Ugur
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Technical Advance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936300/
https://ncbi.nlm.nih.gov/pubmed/27389414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2476-x
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