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A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2C(ATPase) Causes Conditional Defects in Encapsidation and Uncoating

The specificity of encapsidation of C-cluster enteroviruses depends on an interaction between capsid proteins and nonstructural protein 2C(ATPase). In particular, residue N(252) of poliovirus 2C(ATPase) interacts with VP3 of coxsackievirus A20, in the context of a chimeric virus. Poliovirus 2C(ATPas...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Asare, Emmanuel, Mugavero, JoAnn, Jiang, Ping, Wimmer, Eckard, Paul, Aniko V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936127/
https://ncbi.nlm.nih.gov/pubmed/27076638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02877-15
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