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Alanine Scanning of Poliovirus 2C(ATPase) Reveals New Genetic Evidence that Capsid Protein/2C(ATPase) Interactions Are Essential for Morphogenesis

Polypeptide 2C(ATPase) is one of the most thoroughly studied but least understood proteins in the life cycle of poliovirus. Within the protein, multiple functional domains important for uncoating, host cell membrane alterations, and RNA replication and encapsidation have previously been identified....

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Detalhes bibliográficos
Main Authors: Wang, Chunling, Jiang, Ping, Sand, Claire, Paul, Aniko V., Wimmer, Eckard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446611/
https://ncbi.nlm.nih.gov/pubmed/22761387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00914-12
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