The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity

Host responses against metazoan parasites or an array of environmental substances elicit type 2 immunity. Despite its protective function, type 2 immunity also drives allergic diseases. The mechanisms that regulate the magnitude of the type 2 response remain largely unknown. Here, we show that genet...

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Vydáno v:Science
Hlavní autoři: Chan, Pamela Y., Carrera Silva, Eugenio A., De Kouchkovsky, Dimitri, Joannas, Leonel D., Hao, Liming, Hu, Donglei, Huntsman, Scott, Eng, Celeste, Licona-Limón, Paula, Weinstein, Jason S., Herbert, De’Broski R., Craft, Joseph E., Flavell, Richard A., Repetto, Silvia, Correale, Jorge, Burchard, Esteban G., Torgerson, Dara G., Ghosh, Sourav, Rothlin, Carla V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935984/
https://ncbi.nlm.nih.gov/pubmed/27034374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf1358
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