Structural domains within the HIV-1 mRNA and the ribosomal protein S25 influence cap-independent translation initiation

The 5′leader of the HIV-1 genomic RNA is a multifunctional region that folds into secondary/tertiary structures that regulate multiple processes during viral replication including translation initiation. In this work we examine the internal ribosome entry site (IRES) located in the 5′leader that dri...

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Udgivet i:FEBS J
Main Authors: Carvajal, Felipe, Vallejos, Maricarmen, Walters, Beth A., Contreras, Nataly, Hertz, Marla I., Olivares, Eduardo, Cáceres, C. Joaquín, Pino, Karla, Letelier, Alejandro, Thompson, Sunnie R., López-Lastra, Marcelo
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935617/
https://ncbi.nlm.nih.gov/pubmed/27191820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13756
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