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Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance
DNA-dependent protein kinase (DNA-PK) is a serine/threonine kinase that plays an essential role in the repair of DNA double-strand breaks (DSBs) in the non-homologous end-joining (NHEJ) pathway. The DNA-PK holoenzyme consists of a catalytic subunit (DNA-PKcs) and DNA-binding subunit (Ku70/80, Ku). K...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935567/ https://ncbi.nlm.nih.gov/pubmed/27297111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.06.048 |
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