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Radiation-induced afferent arteriolar endothelial-dependent dysfunction involves decreased epoxygenase metabolites

Chronic kidney disease is a known complication of hematopoietic stem cell transplant (HSCT) and can be caused by irradiation at the time of the HSCT. In our rat model there is a 6- to 8-wk latent period after irradiation that leads to the development of proteinuria, azotemia, and hypertension. The c...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Imig, John D., Hye Khan, Md. Abdul, Sharma, Amit, Fish, Brian L., Mandel, Neil S., Cohen, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935507/
https://ncbi.nlm.nih.gov/pubmed/27106038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00023.2016
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