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Keratin 8 knockdown leads to loss of the chloride transporter DRA in the colon
Keratins (K) are intermediate filament proteins important in protection from stress. The roles of keratins in the intestine are not clear, but K8 knockout (K8(−/−)) mice develop a Th2-type colonic inflammation, epithelial hyperproliferation, and mild diarrhea caused by a keratin level-dependent decr...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935477/ https://ncbi.nlm.nih.gov/pubmed/27125276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00354.2015 |
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