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Keratin 8 knockdown leads to loss of the chloride transporter DRA in the colon
Keratins (K) are intermediate filament proteins important in protection from stress. The roles of keratins in the intestine are not clear, but K8 knockout (K8(−/−)) mice develop a Th2-type colonic inflammation, epithelial hyperproliferation, and mild diarrhea caused by a keratin level-dependent decr...
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| Publicat a: | Am J Physiol Gastrointest Liver Physiol |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935477/ https://ncbi.nlm.nih.gov/pubmed/27125276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00354.2015 |
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