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Tumor necrosis factor alpha promotes the proliferation of human nucleus pulposus cells via nuclear factor-κB, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase

Although tumor necrosis factor alpha (TNF-α) is known to play a critical role in intervertebral disc (IVD) degeneration, the effect of TNF-α on nucleus pulposus (NP) cells has not yet been elucidated. The aim of this study was to explore the effect of TNF-α on proliferation of human NP cells. NP cel...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Wang, Xiao-Hu, Hong, Xin, Zhu, Lei, Wang, Yun-Tao, Bao, Jun-Ping, Liu, Lei, Wang, Feng, Wu, Xiao-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935371/
https://ncbi.nlm.nih.gov/pubmed/25304312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214554533
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