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Ginsenoside Rb1 inhibits matrix metalloproteinase 13 through down-regulating Notch signaling pathway in osteoarthritis

Mounting evidence suggests that an excess of matrix metalloproteinase-13 (MMP-13) plays an important role in the breakdown of extracellular matrix in osteoarthritis (OA). Here, the effects of ginsenoside Rb1 (GRb1) on the expression of MMP-13 in IL-1β-induced SW 1353 chondrosarcoma cells and an expe...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Wang, Wei, Zeng, Li, Wang, Ze-ming, Zhang, Sihan, Rong, Xiao-Feng, Li, Rong-Heng
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935351/
https://ncbi.nlm.nih.gov/pubmed/26062798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215587918
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