Preparation and antitumor effect of a toxin-linked conjugate targeting vascular endothelial growth factor receptor and urokinase plasminogen activator

The aberrant signaling activation of vascular endothelial growth factor receptor (VEGFR) and urokinase plasminogen activator (uPA) is a common characteristic of many tumors, including lung cancer. Accordingly, VEGFR and uPA have emerged as attractive targets for tumor. KDR (Flk-1/VEGFR-2), a member...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Xiang, Ying, Li, Qiying, Huang, Dehong, Tang, Xianjun, Wang, Li, Shi, Yang, Zhang, Wenjun, Yang, Tao, Xiao, Chunyan, Wang, Jianghong
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935313/
https://ncbi.nlm.nih.gov/pubmed/25125500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214547154
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