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Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells
Primary human hepatocytes (PHH) are considered to be the gold standard for in vitro testing of xenobiotic metabolism and hepatotoxicity. However, PHH cultivation in 2D mono-cultures leads to dedifferentiation and a loss of function. It is well known that hepatic non-parenchymal cells (NPC), such as...
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| Publicado no: | Exp Biol Med (Maywood) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935273/ https://ncbi.nlm.nih.gov/pubmed/25394621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214558025 |
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