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The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism

The WW domain-containing oxidoreductase (WWOX) encodes a tumor suppressor that is frequently altered in cancer. WWOX binds several proteins and thus is postulated to be involved in a variety of cellular processes. Interestingly, Wwox-knockout mice develop normally in utero but succumb to hypoglycemi...

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Bibliographic Details
Published in:Exp Biol Med (Maywood)
Main Authors: Abu-Remaileh, Muhannad, Aqeilan, Rami I
Format: Artigo
Language:Inglês
Published: SAGE Publications 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935230/
https://ncbi.nlm.nih.gov/pubmed/25491415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214561956
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