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Alteration of WWOX in human cancer, a clinical view
WWOX gene is located in FRA16D, the highly affected chromosomal fragile site. Its tumor suppressor activity has been proposed on a basis of numerous genomic alterations reported in chromosome 16q23.3–24.1 locus. WWOX is affected in many cancers, showing as high as 80% loss of heterozygosity in breas...
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| I publikationen: | Exp Biol Med (Maywood) |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
SAGE Publications
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935223/ https://ncbi.nlm.nih.gov/pubmed/25681467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214561953 |
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