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The diversity-generating benefits of a prokaryotic adaptive immune system
Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity(1,2). This frequently results in high within-population spacer diversity(3–6), but it is unclear if and why this is important. He...
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| 發表在: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935084/ https://ncbi.nlm.nih.gov/pubmed/27074511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17436 |
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