The diversity-generating benefits of a prokaryotic adaptive immune system

Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity(1,2). This frequently results in high within-population spacer diversity(3–6), but it is unclear if and why this is important. He...

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Bibliografski detalji
Izdano u:Nature
Glavni autori: van Houte, Stineke, Ekroth, Alice K. E., Broniewski, Jenny M., Chabas, Hélène, Ashby, Ben, Bondy-Denomy, Joseph, Gandon, Sylvain, Boots, Mike, Paterson, Steve, Buckling, Angus, Westra, Edze R.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935084/
https://ncbi.nlm.nih.gov/pubmed/27074511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17436
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