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Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats

BACKGROUND AND AIMS: Although the beneficial effects of statins on stroke have been widely demonstrated both in experimental studies and in clinical trials, the aim of this study is to prepare and characterize a new liposomal delivery system that encapsulates simvastatin to improve its delivery into...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Campos-Martorell, Mireia, Cano-Sarabia, Mary, Simats, Alba, Hernández-Guillamon, Mar, Rosell, Anna, Maspoch, Daniel, Montaner, Joan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935044/
https://ncbi.nlm.nih.gov/pubmed/27418824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S107292
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