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Metabolism, Protein Binding, and Renal Clearance of Microbiota–Derived p-Cresol in Patients with CKD
BACKGROUND AND OBJECTIVES: Colonic microbial metabolism substantially contributes to uremic retention solutes in CKD. p-Cresyl sulfate is the main representative of this group of solutes, relating to adverse outcomes. Other than sulfate conjugation, p-cresol is subjected to endogenous glucuronide co...
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| Опубликовано в: : | Clin J Am Soc Nephrol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934829/ https://ncbi.nlm.nih.gov/pubmed/27084876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.00160116 |
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