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Maternal Age at Delivery Is Associated with an Epigenetic Signature in Both Newborns and Adults

Offspring of older mothers are at increased risk of adverse birth outcomes, childhood cancers, type 1 diabetes, and neurodevelopmental disorders. The underlying biologic mechanisms for most of these associations remain obscure. One possibility is that maternal aging may produce lasting changes in th...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Markunas, Christina A., Wilcox, Allen J., Xu, Zongli, Joubert, Bonnie R., Harlid, Sophia, Panduri, Vijayalakshmi, Håberg, Siri E., Nystad, Wenche, London, Stephanie J., Sandler, Dale P., Lie, Rolv T., Wade, Paul A., Taylor, Jack A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934688/
https://ncbi.nlm.nih.gov/pubmed/27383059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156361
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