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Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero

BACKGROUND: Children exposed to maternal smoking during pregnancy exhibit increased risk for many adverse health effects. Maternal smoking influences methylation in newborns at specific CpG sites (CpGs). Here, we extend evaluation of individual CpGs to gene-level and pathway-level analyses among 106...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Rotroff, Daniel M., Joubert, Bonnie R., Marvel, Skylar W., Håberg, Siri E., Wu, Michael C., Nilsen, Roy M., Ueland, Per M., Nystad, Wenche, London, Stephanie J., Motsinger-Reif, Alison
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124223/
https://ncbi.nlm.nih.gov/pubmed/27887572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3310-1
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