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Protein surface topology-probing by selective chemical modification and mass spectrometric peptide mapping.

Aminoacetylation of lysine residues and the modification of arginine by 1,2-cyclohexanedione to N7,N8-(dihydroxy-1,2-cyclohexylidene)arginine were used for probing the surface topology of hen-eggwhite lysozyme as a model protein. The molecular identification of lysine and arginine modification sites...

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Bibliographic Details
Main Authors: Suckau, D, Mak, M, Przybylski, M
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49346/
https://ncbi.nlm.nih.gov/pubmed/1608973
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