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Characterization of the direct targets of FOXO transcription factors throughout evolution

FOXO transcription factors (FOXOs) are central regulators of lifespan across species, yet they also have cell‐specific functions, including adult stem cell homeostasis and immune function. Direct targets of FOXOs have been identified genome‐wide in several species and cell types. However, whether FO...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Webb, Ashley E., Kundaje, Anshul, Brunet, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933671/
https://ncbi.nlm.nih.gov/pubmed/27061590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12479
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