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Characterization of the direct targets of FOXO transcription factors throughout evolution

FOXO transcription factors (FOXOs) are central regulators of lifespan across species, yet they also have cell‐specific functions, including adult stem cell homeostasis and immune function. Direct targets of FOXOs have been identified genome‐wide in several species and cell types. However, whether FO...

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Vydáno v:Aging Cell
Hlavní autoři: Webb, Ashley E., Kundaje, Anshul, Brunet, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933671/
https://ncbi.nlm.nih.gov/pubmed/27061590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12479
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