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Age‐associated vascular inflammation promotes monocytosis during atherogenesis

Aging leads to a proinflammatory state within the vasculature without disease, yet whether this inflammatory state occurs during atherogenesis remains unclear. Here, we examined how aging impacts atherosclerosis using Ldlr (−/−) mice, an established murine model of atherosclerosis. We found that age...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Du, Wei, Wong, Christine, Song, Yang, Shen, Hua, Mori, Daniel, Rotllan, Noemi, Price, Nathan, Dobrian, Anca D., Meng, Hailong, Kleinstein, Steven H., Fernandez‐Hernando, Carlos, Goldstein, Daniel R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933655/
https://ncbi.nlm.nih.gov/pubmed/27135421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12488
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