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Design and optimization of self-nanoemulsifying drug delivery systems for improved bioavailability of cyclovirobuxine D

BACKGROUND: The main purpose of this research was to design a self-nanoemulsifying drug delivery system (SNEDDS) for improving the bioavailability of cyclovirobuxine D as a poorly water-soluble drug. MATERIALS AND METHODS: Solubility trials, emulsifying studies, and pseudo-ternary phase diagrams wer...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ke, Zhongcheng, Hou, Xuefeng, Jia, Xiao-bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933569/
https://ncbi.nlm.nih.gov/pubmed/27418807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S106356
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