Formulation Development and Bioavailability Evaluation of a Self-Nanoemulsified Drug Delivery System of Oleanolic Acid

This study aims to formulate and evaluate bioavailability of a self-nanoemulsified drug delivery system (SNEDDS) of a poorly water-soluble herbal active component oleanolic acid (OA) for oral delivery. Solubility of OA under different systems was determined for excipient selection purpose. Four form...

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Detalhes bibliográficos
Main Authors: Xi, Jia, Chang, Qi, Chan, Chak K., Meng, Zhao Yu, Wang, Geng Nan, Sun, Jia Bei, Wang, Yi Tao, Tong, Henry H. Y., Zheng, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663680/
https://ncbi.nlm.nih.gov/pubmed/19224372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9190-9
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