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Downregulation of tetrahydrobiopterin inhibits tumor angiogenesis in BALB/c-nu mice with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a highly vascular tumor, and treatment options for patients of advanced-stage are limited. Nitric oxide (NO), which is derived from endothelial nitric oxide synthase (eNOS), provides crucial signals for angiogenesis in the tumor microenvironment. Tetrahydrobiopterin...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Dai, Youguo, Cui, Jin, Gan, Ping, Li, Weiming
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933545/
https://ncbi.nlm.nih.gov/pubmed/27279530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4850
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