A ketogenic diet increases transport and oxidation of ketone bodies in RG2 and 9L gliomas without affecting tumor growth

BACKGROUND: The dependence of tumor cells, particularly those originating in the brain, on glucose is the target of the ketogenic diet, which creates a plasma nutrient profile similar to fasting: increased levels of ketone bodies and reduced plasma glucose concentrations. The use of ketogenic diets...

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Udgivet i:Neuro Oncol
Main Authors: De Feyter, Henk M., Behar, Kevin L., Rao, Jyotsna U., Madden-Hennessey, Kirby, Ip, Kevan L., Hyder, Fahmeed, Drewes, Lester R., Geschwind, Jean-François, de Graaf, Robin A., Rothman, Douglas L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933488/
https://ncbi.nlm.nih.gov/pubmed/27142056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now088
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