Cross-talk between Dopachrome Tautomerase and Caveolin-1 Is Melanoma Cell Phenotype-specific and Potentially Involved in Tumor Progression

l-Dopachrome tautomerase (l-DCT), also called tyrosinase-related protein-2 (TRP-2), is a melanoma antigen overexpressed in most chemo-/radiotherapeutic stress-resistant tumor clones, and caveolin-1 (CAV1) is a main regulator of numerous signaling processes. A structural and functional relationship b...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Popa, Ioana L., Milac, Adina L., Sima, Livia E., Alexandru, Petruta R., Pastrama, Florin, Munteanu, Cristian V. A., Negroiu, Gabriela
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933476/
https://ncbi.nlm.nih.gov/pubmed/27053106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714733
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