The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions

TNF-stimulated gene-6 (TSG-6) is a multifunctional protein secreted in response to pro-inflammatory stimuli by a wide range of cells, including neutrophils, monocytes, and endothelial cells. It has been shown to mediate anti-inflammatory and protective effects when administered in disease models, in...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Dyer, Douglas P., Salanga, Catherina L., Johns, Scott C., Valdambrini, Elena, Fuster, Mark M., Milner, Caroline M., Day, Anthony J., Handel, Tracy M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933465/
https://ncbi.nlm.nih.gov/pubmed/27044744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720953
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