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Multiple Glycosaminoglycan-binding Epitopes of Monocyte Chemoattractant Protein-3/CCL7 Enable It to Function as a Non-oligomerizing Chemokine

The interaction of chemokines with glycosaminoglycans (GAGs) facilitates the formation of localized chemokine gradients that provide directional signals for migrating cells. In this study, we set out to understand the structural basis and impact of the differing oligomerization propensities of the c...

詳細記述

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書誌詳細
主要な著者: Salanga, Catherina L., Dyer, Douglas P., Kiselar, Janna G., Gupta, Sayan, Chance, Mark R., Handel, Tracy M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031540/
https://ncbi.nlm.nih.gov/pubmed/24727473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.547737
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