Multiple Glycosaminoglycan-binding Epitopes of Monocyte Chemoattractant Protein-3/CCL7 Enable It to Function as a Non-oligomerizing Chemokine

The interaction of chemokines with glycosaminoglycans (GAGs) facilitates the formation of localized chemokine gradients that provide directional signals for migrating cells. In this study, we set out to understand the structural basis and impact of the differing oligomerization propensities of the c...

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Detaylı Bibliyografya
Asıl Yazarlar: Salanga, Catherina L., Dyer, Douglas P., Kiselar, Janna G., Gupta, Sayan, Chance, Mark R., Handel, Tracy M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031540/
https://ncbi.nlm.nih.gov/pubmed/24727473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.547737
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